The Vaccine Communication Playbook for Pharmacies

Practical tools and guidance to help you build confidence and support vaccine conversations.

Resources for your day

Use this as your daily starting point for clinical references, vaccine schedules, recommendations, and professional updates to support vaccine conversations and decisions during a pharmacy shift.

Clinical references and support
Clinical Pharmacology
Drug information & patient counseling
Lexidrug (Lexicomp)
Drug information & interactions
Micromedex
Drug & disease reference
UpToDate
Clinical decision support
OpenEvidence
Evidence-based clinical answers
When you need vaccine schedules
AAP schedule
American Academy of Pediatrics
ACOG maternal immunization schedule
American College of Obstetricians & Gynecologists
AAFP schedules and resources
American Academy of Family Physicians
CDC immunization schedules
Centers for Disease Control and Prevention
Stay updated on professional guidance
APhA Immunization Center
American Pharmacists Association
NCPA
National Community Pharmacists Association
Conversation guide: Influenza and COVID-19
American Pharmacists Association
Addressing what consumers want to know
American Pharmacists Association

Respond to patient questions

Find brief, ready-to-use responses to the questions and concerns pharmacy staff hear most often. Browse general vaccine questions or select a vaccine for specific concerns. This section is updated as new questions and patterns emerge.

"I'll think about it."
  • Getting vaccinated today means you can take care of it while you are already here.
  • What questions can I answer before you decide?
"I don't have time."
  • The appointment usually takes only a few minutes.
  • Getting it today saves you from making another trip, and you'll be protected sooner.
  • I can explain what to expect before we get started.
"I'm healthy. I never get sick."
  • I'm glad you're healthy.
  • Vaccines help protect you before you're exposed, not after you start feeling sick.
  • Vaccines may also lower the chance of passing an illness to someone who could become very sick.
"My doctor never mentioned it."
  • That can happen. Different health care settings may focus on different vaccines.
  • Pharmacists also review vaccine recommendations based on age and health history.
  • I can explain why this vaccine may be recommended for you.
"I got sick after my last vaccine."
  • I'm sorry you felt sick afterward.
  • Some people can have short-term effects such as a sore arm, tiredness, or a mild fever.
  • That's a sign that your immune system is responding, not that the vaccine gave you the disease.
"Will my insurance cover it?"
  • Coverage can depend on your insurance plan and where you receive the vaccine.
  • Let's check the cost together so you know what to expect before we move forward.
If the patient describes a severe reaction, trouble breathing, swelling, or another concerning symptom, involve the pharmacist rather than using a standard response.

The AIMS approach to conversations

A strong recommendation is one of the most important factors in whether a patient gets vaccinated. Every vaccine conversation begins with a presumptive recommendation. If the patient has questions or concerns, AIMS helps you respond while strengthening trust. The four steps help you make a clear recommendation, understand the patient’s concern, show that you heard it, and identify the next step. You won’t need all four steps in every conversation. Start with Announce, then use the steps that fit each patient’s response.

Select Announce, Inquire, Mirror, or Secure below to view guidance and examples for each step.

VACCINATION IS NOT THE ONLY POSITIVE OUTCOME

A positive outcome may be:

  • The patient chooses to get vaccinated today.
  • The patient leaves feeling heard and respected, with the door open to future conversations.

Select a step above to view its detailed guidance.

Previous step

About the Playbook

The Pharmacy Playbook is a digital point-of-care resource for pharmacy teams. It provides ready-to-use responses, a structured conversation approach, and links to clinical guidance for use during patient interactions. The Playbook was informed by research with pharmacists and pharmacy technicians. It is designed for quick reference and updated regularly to reflect timely vaccine questions and concerns.

The Playbook was developed by the Trusted Messenger Program in partnership with the American Pharmacists Association and the National Community Pharmacists Association, with support from Pfizer.

Want to learn more?

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Download the Playbook as a PDF